The Effect of Wnt5a Signaling on Macrophage Phenotype

Presenter Information

Brakstin Hockley

Abstract

The Wnt5a gene has been shown to have both tumor-suppressive and tumor-progressive activities in human cancers. To better understand its function in the tumor microenvironment, the effect of Wnt5a protein isoforms on macrophages was studied in vitro.

Keywords:

molecular biology, macrophages, Wnt5a, tumor microenvironment

Status

Undergraduate

Department

Biomedical Sciences

College

College of Arts and Sciences

Campus

Athens

Faculty Mentor

Coschigano, Karen

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The Effect of Wnt5a Signaling on Macrophage Phenotype

The Wnt5a gene has been shown to have both tumor-suppressive and tumor-progressive activities in human cancers. To better understand its function in the tumor microenvironment, the effect of Wnt5a protein isoforms on macrophages was studied in vitro.