Inhibition of CXCL10 Expression in PBMCs Exposed to SARS-CoV-2 Spike Protein
Abstract
Overexpression of inflammatory proteins (e.g. CXCL10) in response to SARS-CoV-2 can sometimes lead to severe COVID-19. We have identified a compound that inhibits CXCL10 expression by a subset of leukocytes in an in vitro model of SARS-CoV-2 infection.
Keywords:
Biomedical Engineering, COVID-19, CXCL10, PBMC, Cytokine Storm
Status
Graduate
Department
Chemical and Biomolecular Engineering
College
Russ College of Engineering and Technology
Campus
Athens
Faculty Mentor
Goetz, Douglas
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Inhibition of CXCL10 Expression in PBMCs Exposed to SARS-CoV-2 Spike Protein
Overexpression of inflammatory proteins (e.g. CXCL10) in response to SARS-CoV-2 can sometimes lead to severe COVID-19. We have identified a compound that inhibits CXCL10 expression by a subset of leukocytes in an in vitro model of SARS-CoV-2 infection.