RNA-TARGETED DRUG DESIGN: IMPACT OF pH ON FRAGMENT-BASED LIGAND DISCOVERY
Author ORCID
Abstract
This study investigates possible nucleobase protonation effects on the bacterial T box riboswitch targeted drug discovery by combining structure analysis, computational docking and experimental techniques to understand the impact of pH on RNA-fragment based drug design.
Status
Graduate
Department
Chemistry & Biochemistry
College
College of Arts and Sciences
Campus
Athens
Faculty Mentor
Jennifer Hines
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
RNA-TARGETED DRUG DESIGN: IMPACT OF pH ON FRAGMENT-BASED LIGAND DISCOVERY
This study investigates possible nucleobase protonation effects on the bacterial T box riboswitch targeted drug discovery by combining structure analysis, computational docking and experimental techniques to understand the impact of pH on RNA-fragment based drug design.
