Potent MSB-61 as Type 1 Diabetes (T1D) therapy: mechanism of action in insulin secretion

Presenter Information

Nida Ajmal

Abstract

MSB-61, a novel potent therapeutic compound for Type 1 Diabetes, potentiates insulin secretion. Furthermore, RNA sequencing of MSB-61 uncovered a unique GTPase switch that primarily remains active, suggesting a correlation between the two.

Keywords:

Type 1 diabetes, insulin, beta cells, drug discovery, pathways

Status

Graduate

Department

Translational Biomedical Sciences

College

Heritage College of Osteopathic Medicine

Campus

Athens

Faculty Mentor

Nunemaker, Craig

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Potent MSB-61 as Type 1 Diabetes (T1D) therapy: mechanism of action in insulin secretion

MSB-61, a novel potent therapeutic compound for Type 1 Diabetes, potentiates insulin secretion. Furthermore, RNA sequencing of MSB-61 uncovered a unique GTPase switch that primarily remains active, suggesting a correlation between the two.