Investigating the Mechanism of action of Type 1 Diabetes Therapeutic Compound MSB-61 via RNA Sequencing.
Abstract
MSB-61 protects beta cells of pancreatic islets from cytokine and endoplasmic reticulum-induced cell death by interacting with orphan nuclear receptors and restoring their insulin secretion capacity thus, has the potential to treat Type 1 Diabetes.
Keywords:
Biomedical Sciences, Type 1 Diabetes, Pancreatic islets, ER stress, orphan nuclear receptor
Status
Graduate
Department
Biomedical Sciences
College
College of Arts and Sciences
Campus
Athens
Faculty Mentor
Nunemaker, Craig
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Investigating the Mechanism of action of Type 1 Diabetes Therapeutic Compound MSB-61 via RNA Sequencing.
MSB-61 protects beta cells of pancreatic islets from cytokine and endoplasmic reticulum-induced cell death by interacting with orphan nuclear receptors and restoring their insulin secretion capacity thus, has the potential to treat Type 1 Diabetes.