Impact of Sirt5 Conditional Knockout on Post-Traumatic Osteoarthritis Induced by Non-Invasive ACL Rupture in Obese Mice
Abstract
This study investigates the impact of Sirt5 conditional knockout on the progression of post-traumatic osteoarthritis in obese mice following non-invasive ACL rupture, focusing on pain sensitivity, cartilage degradation, and metabolic disruptions to identify potential therapeutic targets.
Status
Undergraduate
Department
Biological Sciences
College
Honors Tutorial College
Campus
Athens
Faculty Mentor
Zhu, Shouan
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Impact of Sirt5 Conditional Knockout on Post-Traumatic Osteoarthritis Induced by Non-Invasive ACL Rupture in Obese Mice
This study investigates the impact of Sirt5 conditional knockout on the progression of post-traumatic osteoarthritis in obese mice following non-invasive ACL rupture, focusing on pain sensitivity, cartilage degradation, and metabolic disruptions to identify potential therapeutic targets.