Novel peptide based antagonists for the human growth hormone receptor
Abstract
Existing literature have shown that the reduced activity of growth hormone (GH) has a positive correlation with the development of enhanced resistance to GH-related disorders such as diabetes and cancer. Thus, the Holub lab developed a library of stapled peptide hGHR antagonists which resulted in lowering the GH activity in-vitro.
Status
Graduate
Department
Chemistry & Biochemistry
College
College of Arts and Sciences
Campus
Athens
Faculty Mentor
Holub Justin
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Novel peptide based antagonists for the human growth hormone receptor
Existing literature have shown that the reduced activity of growth hormone (GH) has a positive correlation with the development of enhanced resistance to GH-related disorders such as diabetes and cancer. Thus, the Holub lab developed a library of stapled peptide hGHR antagonists which resulted in lowering the GH activity in-vitro.