Presenter Information

Brakstin Hockley

Abstract

In this project we demonstrate that the expression of key cytokines and cluster of differentiation receptors in an in vitro model of tumor-infilitrating macrophages is altered at both the mRNA and protein level after exposure to the Wnt5a isoforms, Wnt5a-Short and Wnt5a-Long.

Status

Undergraduate

Department

Biological Sciences

College

College of Arts and Sciences

Campus

Athens

Faculty Mentor

Karen Coschigano

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Cell signaling via two Wnt-5a protein isoforms alters the immune-signaling profile of tumor-infiltrating macrophages in vitro

In this project we demonstrate that the expression of key cytokines and cluster of differentiation receptors in an in vitro model of tumor-infilitrating macrophages is altered at both the mRNA and protein level after exposure to the Wnt5a isoforms, Wnt5a-Short and Wnt5a-Long.