Title

ATG8-Binding UIM Proteins Define a New Class of Autophagy Adaptors and Receptors

Document Type

Article

Publication Date

4-18-2019

Abstract

© 2019 Elsevier Inc. Across organisms, the key autophagy protein ATG8/LC3 binds a group of proteins on a site distinct from its classical interacting region, raising the possibility of dual binding interactions and identifying an array of previously unknown selective autophagic adaptors and receptors, including some involved in human disease.

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